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Scientific Communications: SAH, aneurysms and vascular malformations 02.00 - INTRACRANIAL HEMORRHAGE - 02.02 - SAH, ANEURYSMS AND VASCULAR MALFORMATIONS O - ESOC25-1352 SEX-SPECIFIC DNA METHYLATION SIGNATURE OF ANEURYSMAL SUBARACHNOID HEMORRHAGE Adri MacIas-Gmez 1 , Joan Jimnez-Balado 1 , Isabel Fernndez-Prez 1,2 , Antoni Surez-Prez 1 , Marta Vallverd-Prats 1 , Sergio Vidal-Notari 2 , Julia Peris-Subiza 2 , Laia Peraferrer-Montesinos 2 , Daniel Guisado-Alonso 1 , Eva Giralt-Steinhauer 1,2 , Ana Rodrguez-Campello 1,2 , Angel Ois 1,2 , Jordi Jimnez-Conde 1,2 , Elisa Cuadrado-Godia 1,2 1 Hospital del Mar Research Institute, Barcelona, Spain, 2 Hospital del Mar, Barcelona, Spain Background and Aims: Sex differences in the prevalence of aneurysmal subarachnoid hemorrhage (aSAH) have long been described, and epigenetics might help explain sex-specific pathophysiological mechanisms underlying aSAH