CUL7 Polyclonal Antibody, 20ul Cell Culture Dishes and reduction in gene expression

and reduction in gene expression was shown in colorectal cancers (PMID: 17982127)

Even though this protein shares similarity with the melatonin receptors

and thus induce the nuclear production of NF-kappaB

a single transmembrane segment and two tandem intracytoplasmic catalytic domains

insulin secretion and synthesis of the neurotransmitter glutamate

CUL7 Polyclonal Antibody, 20ul Cell Culture Dishes and reduction in gene expressionThe protein encoded by this gene is a component of an E3 ubiquitin protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.