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This naturally occurring amino acid helps in fat metabolism in the body

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significantly reduces the production of NADPH-dependent O 2 in the kidney

Receptors for microbial metabolites, notably free fatty acid receptors 2 and 3 (FFAR2/GPR43 and FFAR3/GPR41), are expressed on enteroendocrine L-cells and respond to SCFAs by activating vagal afferents, thereby relaying metabolic information to the brain [15,35,36]

While both groups experienced improvements in HbA1c, fasting glucose, and postprandial glucose, participants in the high-fiber group experienced better glycemic control (89% achieved HbA1c 70% max heart rate) is generally recommended