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In the early phases of neuroinflammation, gene expression tends to favor proliferation, whereas in later stages, immune-response genes become predominant, accompanied by the downregulation of homeostatic genes responsible for structural integrity, cell adhesion, and receptor function [31, 42, 43]

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[DOI] [PubMed] [Google Scholar] [33].Alehagen U, Aaseth J, Alexander J, Johansson P, Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized double-blind placebo-controlled trial in elderly