GSK429286A - CAS# 864082-47-3 Catalog No.:M6852-C on the growth of hepatocellular

on the growth of hepatocellular carcinoma cell line hepG2]

Acta Pharmacol Sin

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis

Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes

PubMed PMID: 27997653

GSK429286A - CAS# 864082-47-3 Catalog No.:M6852-C on the growth of hepatocellularGSK429286A, CAS No. 864082 47 3, is a selective Rho kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin induced contraction of the rat aortic ring (IC50 = 190 nM) and causes a dose dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats. Orally active. Product information CAS Number: 864082 47 3 Molecular Weight: 432. 37 Formula: C21H16F4N4O2 Synonym: GSK 429286A