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The post argues non-response is usually a combination of these rather than a simple drug failure

Options include: Metoclopramide : May help with delayed gastric emptying but should only be used for short courses (maximum 5 days) due to risk of neurological side effects Prochlorperazine : Can be effective for nausea and vomiting Cyclizine : An alternative that works through a different mechanism Ondansetron : Sometimes used but may cause constipation Domperidone : Used cautiously due to risk of heart rhythm problems (QT prolongation), particularly in older adults, those with heart conditions, or those taking other medications affecting heart rhythm For people with diabetes, it's important to follow sick-day rules if experiencing vomiting

documented a significant survival improvement in 581 men with T2DM treated with T for six years [69]

Only 19% of large employers covered GLP-1s for weight loss in 2025, and many are reducing coverage due to costs

Some of them require prior authorization processes

Symptoms of delayed gastric emptying, nausea and vomiting are listed as side effects," the statement continued