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Considering the microbiotagutbrain axis, a healthier microbiome and improved gut barrier function have been associated with better psychiatric outcomes [93]

Results show that GLP-1RA users, defined as individuals with a history of use exceeding six months and with at least two refills within six months prior to the procedure, experienced a higher incidence rate of aspiration pneumonia (0.83%) compared to nonusers (0.63%), corresponding to a hazard ratio of 1.33

Patients are advised to use barrier contraception or switch to non-oral methods during the initiation phase and for 4 weeks following each dose escalation

Clinical trials for SGLT2 inhibitors show a clear and significant increase in the risk of genital yeast infections in both men and women