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MPEP Hydrochloride - CAS# 219911-35-0 Catalog No.:M10378-2 also known as Pelabresib

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MPEP Hydrochloride - CAS# 219911-35-0 Catalog No.:M10378-2 also known as PelabresibMPEP is a selective mGluR5 antagonist. MPEP reverses maze learning and PSD 95 deficits in Fmr1 knock out mice. MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine sensitive glycine receptors. MPEP activates specific stress related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK 801: significance for the use as anxiolytic antidepressant drug. Product information CAS Number: 219911 35 0 Molecular

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Description

also known as Pelabresib

2014 Jun 20

Rigosertib is non-ATP-competitive inhibitor to PLK1 with IC50 of 9 nM

Chemical Name: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N

Solubility: DMSO: 100 mg/mL(108

MPEP Hydrochloride - CAS# 219911-35-0 Catalog No.:M10378-2 also known as PelabresibMPEP is a selective mGluR5 antagonist. MPEP reverses maze learning and PSD 95 deficits in Fmr1 knock out mice. MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine sensitive glycine receptors. MPEP activates specific stress related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK 801: significance for the use as anxiolytic antidepressant drug. Product information CAS Number: 219911 35 0 Molecular

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