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Start your intake Why Semaglutide and GLP-1 Medications Make You Feel Cold GLP-1 receptor agonists like semaglutide work by slowing digestion and reducing appetite, which lowers overall calorie intake and accelerates fat loss

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These side effects are most common in the first days and weeks after beginning GLP-1 therapy or after increasing dosage, but for some patients, they may persist for longer

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Because it is an FDA approved medication, clinicians can provide specific guidance on dosing based on decades of clinical trials, providing a clear path from intake to expected physiological changes