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Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats

doi: 10.1016/j.jacbts.2018.09.004 137 GastaldelliACusiK

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Severe dysarthria, spasmodic dysphonia, and tongue fasciculations, along with muscle atrophy in the bilateral intrinsic hand muscles