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Mechanistic evidence has indicated that GLP-1RAs promote bone marrow-derived macrophage polarization into the M2 phenotype via the cAMP-PKA-signal transducers and activators of the transcription 3 (STAT3) pathway [137, 138]

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These brain areas include the hippocampus, prefrontal cortex, striatum, and substantia nigra, which are all implicated in attention, impulse control, and motivationfunctions that are often impaired in attention deficit hyperactivity disorder (ADHD)

To our knowledge, many studies have been carried out in loading of cancer drugs, such as doxorubicin and camptothecin, onto GO functionalised with an antibody for theranostic of cancer cells 42,43