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Obviously, we're aware of the cumulative economic impact that builds every week that it lasts

These symptoms occurred largely during the dose-escalation period, were transient and mild/moderate in severity, and led to drug discontinuation in up to 7% of participants in each active therapy group

Compared to Bydureon or Exenatide Extended Release the 1mg dose lowered the HbA1C by about 1.5% compared to Exenatide at 0.9% so there was about a 0.6% reduction but Ozempic was superior

Importantly, these medications carry a boxed warning about the risk of thyroid C-cell tumors and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

[DOI] [PMC free article] [PubMed] [Google Scholar] Mitchell JR, Jollow DJ, Potter WZ, Gillette JR, Brodie BB