AVP Receptor V2 Polyclonal Antibody, 20ul[BT-AP06610] Antibody Development Mutations in this gene result

Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2| and loss of heterozygosity of this gene is implicated in breast cancer

Both genes are associated with susceptibility to leprosy

The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit

ISL2 is a Protein Coding gene

AVP Receptor V2 Polyclonal Antibody, 20ul[BT-AP06610] Antibody Development Mutations in this gene resultThis gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven transmembrane domain G protein coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non mammals, is well conserved, though several members signal via other G