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B12 supplementation in elderly patients with confirmed deficiency typically takes two main forms in the UK: Oral tablets (cyanocobalamin) Intramuscular injections (hydroxocobalamin, the standard form in the UK) NICE Clinical Knowledge Summary guidance recommends investigating B12 deficiency in older adults presenting with unexplained anaemia, neuropathy, cognitive impairment, or glossitis

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This schedule uses the largest practical dilution (3.0 mL) to keep perinjection units 10 for better accuracy

Extremes matter: patients under 50 kg often do well at the lower end, patients over 100 kg may sit at the upper end of standard ranges

In appropriate amounts, it promotes vasodilation, enhances blood flow, and supports healing

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