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HVF testing showed the progression of the altitudinal defect, with a deep scotoma in the inferotemporal quadrant, diffuse involvement of the inferonasal quadrant, and extension into the central field (Figure 1B)

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Accumulation of misfolded proteins increases the production of BiP/GRP78, which initiates XBP1 splicing and induces ATF6 signaling (64, 65)

GLP-1 receptor agonists, such as liraglutide, show promise in treating non-alcoholic fatty liver disease (NAFLD), particularly in individuals with type 2 diabetes (T2DM) and obesity

There was also a tentative observation of increased epithelialization, a process essential for the regeneration of the skin's outer layer, in these experimental conditions

This leads to NF-B-mediated expression of pro-inflammatory cytokines (IL-6 and TNF-), constituting a core mechanism of acute gout attacks