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However, autophagy is essentially a protective response in the face of cellular stress, and defective autophagy increases melanocyte sensitivity to oxidative stress (75)

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The read mapping, variant calling and joint variant calling were performed using Sentieons DNASeq pipeline v.201808.03, following the BWA-GATK Best Practice Workflow and using the GRCh38/hg38 reference genome

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The homogenized lysate was then run through QIAshredder columns (Qiagen, 79656)