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The reduced fraction of Mia40 cannot contribute to oxidation of proteins, but might for example be involved in isomerization of more complex substrates, in deglutathionylation of proteins, in reduction of proteins prior to their degradation, or in reduction of proteins to regulate their activity

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Schistosomula were assessed daily for viability by microscopy

Recent advancements in structural biology and electrophysiology have shed light on the molecular architecture governing MIC activation, demonstrating that force-induced conformational changes within channel domains, along with their dynamic interactions with cytoskeletal components, dictate the gating behavior in response to mechanical stress

(2024) 357:e2300569

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