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Implications of Glutathione Deficiency A glutathione deficiency has been linked to several digestive-related conditions, such as leaky gut (mentioned above) as well as gut dysbiosis and chronic inflammation

As the disease advances, ferroptosis-induced release of damage-associated molecular patterns (DAMPs), exosomal transmission, and immune evasion mechanisms further amplify neuroinflammation and cell damage, establishing a cascade of intercellular pathological propagation that accelerates neurodegeneration

While the ligand-binding function remains unclear, sequestering molecules may serve a regulatory role, preventing cytotoxic ligands from interacting with their targets

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