HIF-1 Alpha Monoclonal Antibody, 50ul Gel & Buffers Autosomal recessive hypothalamic corticotropin deficiency

Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis

Caspase 8 is involved in the programmed cell death induced by Fas and various apoptotic stimuli

CREB1 encodes a transcription factor (cAMP responsive element binding protein 1) that is a member of the leucine zipper family of DNA binding proteins

The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal

Defects in this gene are a cause of susceptibility to endometrial cancer

HIF-1 Alpha Monoclonal Antibody, 50ul Gel & Buffers Autosomal recessive hypothalamic corticotropin deficiencyThis gene encodes the alpha subunit of transcription factor hypoxia inducible factor 1 (HIF 1), which is a heterodimer composed of an alpha and a beta subunit. HIF 1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate