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GR constitutes ~ 5%10% of total GR transcripts, has shown impaired transactivation activity, and has been proposed to regulate mitochondrial homeostasis (24, 25)

It consists of all the messenger RNA (mRNA), transfer RNA (tRNA), ribosomal RNA (rRNA) and non-coding RNA pooled together which represents the active RNA component in a genome

10.1016/S1360-1385(01)01961-6 104 MaestriE.MarmiroliM.VisioliG.MarmiroliN

This finding aligns with evidence from large trials in T2DMsuch as LEADER, REWIND, and AMPLITUDE-Owhich reported death reductions ranging from 12 to 22% [10, 22]

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Mobilisation des graisses stockes En facilitant le transport des acides gras vers les mitochondries, la L-Carnitine favorise leur utilisation directe comme source dnergie