Apilimod - CAS# 541550-19-0 Size:Solid 10 mg the molecular target of folate

the molecular target of folate antagonist-type chemotherapeutic drugs

not IKZF1/3

[2H]C([2H])([2H])N1CCC(CC1)C1=CNC2=CC=C(CCS(=O)(=O)NC)C=C12

Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM

N-bis(2-chloroethyl)-4-(3-{6-[6-(4-methylpiperazin-1-yl)-1H-1

Apilimod - CAS# 541550-19-0 Size:Solid 10 mg the molecular target of folateApilimod, also known as STA 5326, is a IL 12 IL 23 inhibitor. Apilimod inhibits IL 12 and IL 23 production cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL 12 and IL 23 production by the drug.