Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter Accumulation of EXPAND1/MUM1 at damaged
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Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter Accumulation of EXPAND1/MUM1 at damagedStable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1 or separase which
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