Bax Polyclonal Antibody, 100ul[BT-AP00846] Custom RNA Oligos Since lens central fiber cells

Since lens central fiber cells lose their nuclei during development| these crystallins are made and then retained throughout life| making them extremely stable proteins

Mutations in PAX8 have been associated with thyroid dysgenesis

and inhibition of protein kinase C-mediated phosphorylation

Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production

The product of this gene is required for stem-cell maintenance in the central nervous system| and also regulates gene expression in the stomach

Bax Polyclonal Antibody, 100ul[BT-AP00846] Custom RNA Oligos Since lens central fiber cellsThe protein encoded by BAX belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. This protein (BCL2 associated X, apoptosis regulator) forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage dependent anion