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Below is a balanced view that reflects both research findings and clinical experience

For safety reasons, oral semaglutide is not recommended for people with a personal or family history of medullary thyroid cancer or certain genetic endocrine disorders

Endocrinology 141: 3703-3709, 2000

Dora Matis - April 13, 2026 GLP-1 receptor agonists such as semaglutide-based medications support blood sugar control, weight loss, and cardiovascular health through effects on insulin, appetite, and gastric emptying