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4:10 Treatment Considerations Some mood stabilizers mainly achieve and sustain euthymia by virtue of their antimanic properties

restart XIGDUO XR if renal function is stable [see Warnings and Precautions (5.1)]

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Patients with high-response genetic markers may achieve meaningful weight loss at 0.5 mg or 1.0 mg, allowing them to skip or shorten higher doses and reduce side effect burden