Rad18 Polyclonal Antibody, 50ul Bottle-Top Dispenser SLC25A44 belongs to the SLC25

SLC25A44 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al

Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency

The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression

post-translational processing

This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat

Rad18 Polyclonal Antibody, 50ul Bottle-Top Dispenser SLC25A44 belongs to the SLC25RAD18, E3 ubiquitin protein ligase encoded by RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin conjugating enzyme required for post replication repair of damaged DNA. Similar to its yeast counterpart, RAD18, E3 ubiquitin protein ligase is able to interact with the human homolog of yeast Rad6 protein through a conserved ring finger motif. Mutation of