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DHEA has been shown to increase the numbers of natural killer cells in aging women

Murphy JV, Marquardt KM, Shug AL: Valproic acid associated abnormalities of carnitine metabolism

A., Prez-Martos, A., Montoya, J

This explains why some patients experience: Temporary bloating or joint discomfort from fluid shifts Increased hunger due to ghrelin pathway activation Changes in blood sugar regulation in susceptible individuals Patients with diabetes, insulin resistance, or other metabolic conditions require medical evaluation and appropriate monitoring before and during treatment