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Nectin 3 Polyclonal Antibody, 100ul[BT-AP05869] Gene Editing a characteristic unique to this

SKU: 77556591853

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Nectin 3 Polyclonal Antibody, 100ul[BT-AP05869] Gene Editing a characteristic unique to thisPVRL3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin like proteins and with afadin, a filamentous actin binding protein involved in the regulation of directional motility, cell proliferation and survival. PVRL3 plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular

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Description

a characteristic unique to this subfamily

In conjunction with p38 MAP kinase| this kinase is known to be involved in many cellular processes including stress and inflammatory responses| nuclear export| gene expression regulation and cell proliferation

This enzyme is demonstrated to participate in the ubiquitination of p53

Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion

In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation

Nectin 3 Polyclonal Antibody, 100ul[BT-AP05869] Gene Editing a characteristic unique to thisPVRL3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin like proteins and with afadin, a filamentous actin binding protein involved in the regulation of directional motility, cell proliferation and survival. PVRL3 plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular

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