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Paxillin(Phospho Ser272) Polyclonal Antibody, 20ul Miscellaneous This gene is expressed at

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Paxillin(Phospho Ser272) Polyclonal Antibody, 20ul Miscellaneous This gene is expressed atThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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Description

This gene is expressed at high levels during embryonic development

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis

Lower levels in lung

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

Basigin encoded by BSG is a plasma membrane protein that is important in spermatogenesis

Paxillin(Phospho Ser272) Polyclonal Antibody, 20ul Miscellaneous This gene is expressed atThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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