Ripasudil HCl dihydrate - CAS# 887375-67-9 183 Chronic oral administration of ZLN005

Chronic oral administration of ZLN005 at 15 mg/kg per day to diabetic db/db mice increased PGC-1α and downstream gene transcription in skeletal muscle

PubMed PMID: 27226731

Studies in animals have also found a protection against carcinogens

the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins

4]diazepin-4-yl)-N-ethylacetamide

Ripasudil HCl dihydrate - CAS# 887375-67-9 183 Chronic oral administration of ZLN005Ripasudil HCl dihydrate, CAS No. 887375 67 9, is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively. Product information CAS Number: 887375 67 9 Molecular Weight: 395. 88 Formula: C15H23ClFN3O4S Synonym: K 155 K115 Glanatec Ripasudil HCl dihydrate Related CAS Number: 223644 02 8 (HCl) 223645 67 8 (free base) Chemical Name: (S) 4 fluoro 5 ((2 methyl 1,4 diazepan 1 yl)sulfonyl)isoquinoline hydrochloride dihydrate