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4 Of the two dominant incretins, GIP has been shown to have a greater effect on insulin release following oral glucose ingestion in healthy humans

TSHR signaling in OFs induces miR-146a and miR-155, inhibiting ZNRF3 and PTEN to promote fibroblast expansion, while genetic variants of TSHR may enhance its antigenic role in OFs even before adipogenesis, further implicating TSHR in TAO pathogenesis [292, 293]

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Composed of the amino acids cysteine, glutamic acid, and glycine, gamma-glutamyl-L-cysteinyl glycine, or glutathione (GSH), is a tripeptide thiol that's present in large concentrations in the cytosol and organelles of every cell

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