JIP-1(Phospho Thr103) Polyclonal Antibody, 100ul Aspirating Pipets This gene encodes a cell

This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels

It is highly expressed in the adrenal gland and testis

It has a domain organization reminiscent of spliceosomal proteins

Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination

In the rest of the brain a basal expression seems to be always present

JIP-1(Phospho Thr103) Polyclonal Antibody, 100ul Aspirating Pipets This gene encodes a cellThis gene encodes a regulator of the pancreatic beta cell function. It is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA binding transactivator of the glucose