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The Role of GLP-1 Medications in Menopause-Related Weight Gain GLP-1 receptor agonists like semaglutide work by mimicking glucagon-like peptide-1, a natural hormone that signals fullness to the brain, slows stomach emptying, and improves insulin sensitivity

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Clinical data shows that patients typically experience meaningful results within the first month, though individual timelines vary based on starting weight, metabolism, and adherence