LMX1B Polyclonal Antibody, 50ul Shakers PTTG1IP (pituitary tumor-transforming 1 interacting

PTTG1IP (pituitary tumor-transforming 1 interacting protein) encodes a single-pass type I integral membrane protein

Two encoded proteins

Potential regulator of neural basic helix-loop-helix genes

LRRK1 (leucine-rich repeat serine/threonine-protein kinase 1)

This protein is one of over 40 subunits found in complex I

LMX1B Polyclonal Antibody, 50ul Shakers PTTG1IP (pituitary tumor-transforming 1 interactingLMX1B encodes a member of LIM homeodomain family of proteins containing two N terminal zinc binding LIM domains, 1 homeodomain, and a C terminal glutamine rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail patella syndrome.