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A recent study comparing the effects of ten different antiretrovirals with high BBB penetration scores found that cortical nerve termini were not affected, while striatal nerve terminals exhibited reduced mitochondrial spare respiratory capacity for all drugs testes

The improvement is incremental rather than independent

symptoms specifically labelled as 'acid reflux' or 'heartburn' were not consistently reported as discrete adverse event terms in the published data, and readers should interpret any such figures with caution

however, research findings are still limited and inconclusive

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