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In the SURMOUNT-1 clinical trial, participants lost an average of 22.5% of body weight on the 15 mg dose over 72 weeks

Ginger tea, ginger candies, or fresh ginger added to meals may provide relief

Jastreboff et al

These medications help slow gastric emptying, enhance insulin secretion, and reduce appetite so that patients can see more effective results

In the SAVOR study DPP-4 inhibition with saxagliptin did not increase or decrease the rate of ischemic events, though the rate of hospitalization for heart failure was increased [27]