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reduced glutathione, an important intracellular metabolite for regulation, is a prosthetic group of glyceraldehyde phosphate dehydrogenase, is a coenzyme of glyoxalase and triose dehydrogenase, participates in tricarboxylic acid cycle and sugar metabolism in vivo, and can activate various enzymes such as sulfhydryl (-SH) enzyme-coenzyme and the like, thereby promoting carbohydrate, fat and protein metabolism

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an inhibitor of IGF-I action (34), where IGFBP-1 is low during states of hyperinsulinemia but elevated during states of hypoinsulinemia (35)

For each type of PTL, samples were taken to characterize the content of the selected long-lived species (hydrogen peroxide, nitrates, and nitrites)

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